This document outlines health and safety precautions related to COVID-19 that will be used when conducting human-subjects research in the Federal Railroad Administration’s (FRA’s) Cab Technology Integration Lab (CTIL) to protect the health and wellbeing of both experimenters and research participants. Because of the changing nature of the pandemic, this plan may undergo periodic updates to stay current with other guidance (e.g., Federal, State, or facility guidance) or to address any changes the lab deems needed to protect staff and research participants.